发明名称 Method for obtaining the derivatives of 13,14-dihydro-PGF₂α
摘要 The invention relates to a process for the preparation of 13,14-dihydro-PGF2α derivatives of R or S configuration at carbon 15, represented by the general formula (I), wherein the identity of the substituents is defined in the description. Compounds of the formula (I) are valuable biologically-active substances or intermediates in the preparation thereof. The invention especially relates to the process for preparation of 13,14-dihydro-15(R)-17-substituted-18,19,20-trinor-PGF2α, i.e., latanoprost.
申请公布号 PL212658(B1) 申请公布日期 2012.11.30
申请号 PL20050374461 申请日期 2005.04.18
申请人 INSTYTUT FARMACEUTYCZNY 发明人 MARTYNOW JACEK;SZYC JULITA;SZELEJEWSKI WIESLAW;ACHMATOWICZ OSMAN;KUTNER ANDRZEJ;WISNIEWSKI KRZYSZTOF;WINIARSKI JERZY;ZEGROCKA-STENDEL OLIWIA;GOLEBIEWSKI PIOTR
分类号 C07C405/00;C07C317/18 主分类号 C07C405/00
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