| 发明名称 |
COMPOUNDS OF 2-(2-HALOGEN-4-AMINOPHENYL)PYRIDYL INHIBITORS OF HEDGEHOG SIGNALING (EMBODIMENTS), PROCESS FOR PREPARING SAME, COMPOSITION AND METHODS FOR TREATING CANCER AND INHIBITING ANGIOGENESIS AND HEDGEHOG PATHWAY SIGNALING IN CELLS BASED THEREON |
| 摘要 |
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula Iwherein R, Rand m are as described herein. |
| 申请公布号 |
EA017262(B1) |
申请公布日期 |
2012.11.30 |
| 申请号 |
EA20070000538 |
申请日期 |
2005.09.02 |
| 申请人 |
GENENTECH, INC.;CURIS, INC. |
发明人 |
GUNZNER JANET;SUTHERLIN DANIEL;STANLEY MARK;BAO LIANG;CASTANEDO GEORGETTE;LALONDE REBECCA;WANG SHUMEI;REYNOLDS MARK;SAVAGE SCOTT;MALESKY KIMBERLY;DINA MICHAEL |
| 分类号 |
C07D213/40;C07D213/38;C07D213/56;C07D213/70;C07D213/75;C07D213/81;C07D213/82;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D413/12;C07D417/04;C07D417/12;C07F9/142 |
主分类号 |
C07D213/40 |
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