发明名称 PREDICTION OF DEVELOPMENT OF INFANT ATOPIC DERMATITIS ON BASIS OF CYTOKINE/CHEMOKINE IN BREAST MILK
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for elucidating a correlation between a level of various cytokines/chemokines contained in breast milk and an onset of the atopic dermatitis and, on the basis thereof, predicting the infant atopic dermatitis on the basis of cytokine/chemokine values in the breast milk. <P>SOLUTION: The method for determining an onset risk of the infant atopic dermatitis includes: (1) measuring a concentration of at least one cytokine selected from the group comprising IL-1&beta;, IL-6, IL-7, IL-12p40, IL-13, and MIP-1&alpha; in colostrum that an infant takes, or a concentration of at least one cytokine or chemokine selected from the group comprising IL-1&alpha;, IL-4, IL-6, IL-7, IL-12p40, eotaxin, G-CSF, GM-CSF, IFN-&alpha;2, and MIP-1&alpha; in mature milk that the infant takes; and (2) correlating the concentrations of cytokine or chemokine measured in (1) with the onset risk of the infant atopic dermatitis. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012233777(A) 申请公布日期 2012.11.29
申请号 JP20110102014 申请日期 2011.04.28
申请人 CHIBA UNIV 发明人 SHIMOJO NAOKI;KONO YOICHI;SUZUKI YOICHI;OCHIAI SHINGO
分类号 G01N33/53;A61K45/00;A61P17/02;A61P37/08;C07K14/53;C07K14/54;C07K14/56;C07K16/18;C07K16/24;G01N33/15;G01N33/50 主分类号 G01N33/53
代理机构 代理人
主权项
地址