发明名称 |
GENE-EXPRESSION PROFILING WITH REDUCED NUMBERS OF TRANSCRIPT MEASUREMENTS |
摘要 |
<p>The present invention provides compositions and methods for making and using a transcriptome-wide gene-expression profiling platform that measures the expression levels of only a select subset of the total number of transcripts. Because gene expression is believed to be highly correlated, direct measurement of a small number (for example, 1,000) of appropriately- selected transcripts allows the expression levels of the remainder to be inferred. The present invention, therefore, has the potential to reduce the cost and increase the throughput of full- transcriptome gene-expression profiling relative to the well-known conventional approaches that require all transcripts to be measured.</p> |
申请公布号 |
SG184466(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
SG20120074209 |
申请日期 |
2011.04.06 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
LAMB, JUSTIN;GOLUB, TODD, R.;SUBRAMANIAN, ARAVIND;PECK, DAVID, D. |
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