发明名称 |
KINASE INHIBITORS FOR PREVENTING OR TREATING PATHOGEN INFECTION AND METHOD OF USE THEREOF |
摘要 |
The present invention provides compositions and methods of use thereof to prevent and/or treat pathogenic infection. In particular, the present invention provides the use of kinase inhibitors to inhibit kinases that involve in pathogen-host cell interactions that are associated with or cause pathogenic infections, therefore, to effectively prevent and/or treat pathogenic infections with far less likely to engender resistance as compared to conventional antibiotics and anti-viral drugs. The present invention further provides the use of kinase inhibitors for the treatment of acute pathogenic infections for a short period of time to avoid toxicities that may caused by long term use of these kinase inhibitors.
|
申请公布号 |
US2012302565(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
US201213566186 |
申请日期 |
2012.08.03 |
申请人 |
KALMAN DANIEL;BORNMANN WILLIAM;M.D. ANDERSON CANCER CENTER;EMORY UNIVERSITY |
发明人 |
KALMAN DANIEL;BORNMANN WILLIAM |
分类号 |
A61K31/506;A61K31/437;A61K31/5025;A61K31/505;A61K31/5377;A61P31/04;A61P31/06;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22 |
主分类号 |
A61K31/506 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|