摘要 |
Provided are nucleic acids capable of hybridizing to HPV 16 and/or HPV 18 nucleic acids, in particular, mRNA encoding E2 and E6-7 gene products. Such nucleic acids are useful in methods of isolating RNA from a biological sample, methods and means for determining the presence of particular RNA splice-form variants in a biological sample, methods and means for determining the relative ratio of RNA ratios in a biological sample, methods and means for predicting the progression of precancerous cervical lesions, and methods and means for detecting disruption of genes or gene expression. |
申请人 |
QIAGEN GAITHERSBURG, INC.;LOWE, BRIAN;FULBRIGHT, ANNA, K.;NAZARENKO, IRINA |
发明人 |
LOWE, BRIAN;FULBRIGHT, ANNA, K.;NAZARENKO, IRINA |