发明名称 QUINAZOLINE DERIVATIVE AS TYROSINE-KINASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
摘要 The present invention relates to a quinazoline derivative as a tyrosine-kinase inhibitor represented by the general formula (I), the pharmaceutically acceptable salts and stereoisomers thereof and their preparation method for same. The present invention also relates to pharmaceutical compositions and preparations that contain said derivative and the pharmaceutical applications of the derivative in treating and in preparing the treatment of hyperproliferative diseases and chronic obstructive pulmonary disease. The definitions of R1, R2, R3, R3', R4, R5, R6, X, L, T, Z and q in the formula are provided in the description.
申请公布号 WO2012159457(A1) 申请公布日期 2012.11.29
申请号 WO2012CN00737 申请日期 2012.05.28
申请人 KBP BIOSCIENCES CO., LTD.;WU, FRANK;WANG, AICHEN 发明人 WU, FRANK;WANG, AICHEN
分类号 C07D239/94;A61K31/517;A61K31/5377;A61P11/00;A61P35/00;C07D403/12;C07D471/08;C07D471/10 主分类号 C07D239/94
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