发明名称 |
PROCESS FOR SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERADINES |
摘要 |
The present invention provides a highly efficient, versatile one-step process for asymmetric synthesis of either diastereomer of 2-substituted pyrrolidines from a single starting material with excellent yields and high diastereoselectivety. Also provided is a method for the asymmetric synthesis of both diastereomers of 2-substituted piperidines with good yields and excellent diastereoselectivety. Diasteroselectivity is controlled effectively by choice of reducing agent. |
申请公布号 |
US2012302756(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
US201113576427 |
申请日期 |
2011.02.17 |
申请人 |
LELETI RAJENDER REDDY;LIU YUGANG;PRASHAD MAHAVIR |
发明人 |
LELETI RAJENDER REDDY;LIU YUGANG;PRASHAD MAHAVIR |
分类号 |
C07D211/96;C07D203/24 |
主分类号 |
C07D211/96 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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