发明名称 |
Enhanced Stability of Proteins Immobilized on Nanoparticles |
摘要 |
This invention is directed to the application of a previously unknown property of nanomaterials—its ability to enhance protein activity and stability at high temperatures, in organic solvents, and in polymer composites. Nanomaterials such as single-walled carbon nanotubes (SWNTs) can significantly enhance enzyme function and stability in strongly denaturing environments. Experimental results and theoretical analysis reveal that the enhancement in stability is a result of the curvature of these nanoscale materials, which suppresses unfavorable protein-protein interactions. |
申请公布号 |
US2012301870(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
US201213456571 |
申请日期 |
2012.04.26 |
申请人 |
DORDICK JONATHAN S.;KANE RAVINDRA S.;ASURI PRASHANTH;KARAJANAGI SANDEEP S.;VERTEGEL ALEXEY A.;SIEGEL RICHARD W.;RENSSELAER POLYTECHNIC INSTITUTE |
发明人 |
DORDICK JONATHAN S.;KANE RAVINDRA S.;ASURI PRASHANTH;KARAJANAGI SANDEEP S.;VERTEGEL ALEXEY A.;SIEGEL RICHARD W. |
分类号 |
C12N11/00;B82Y15/00;C12N9/96;C12N11/08;C12N11/14;C12Q1/25;C12S9/00 |
主分类号 |
C12N11/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|