| 摘要 |
<p>Provided are new 6-(aryl-carboxamide) imidazo [1,2-a] pyrimidine and 6-(aryl carboxamide) [1,2,4] triazolo [4,3-a] pyrimidine as represented by formula I. Ar, A, and R2-R4 are as defined in the present application. The compound represented in formula I is a Hedgehog pathway inhibitor. Hence, the compound of the present invention can be used for treating diseases caused by abnormal Hedgehog activity, such as cancers.</p> |
| 申请人 |
IMPACT THERAPEUTICS, INC.;CAI, SUIXIONG;TIAN, YE EDWARD;DONG, HAIJUN;XIE, KAI;LI, SICUN;WANG, BIN;ZHANG, XIUYAN;KONG, LINGSHENG;FEI, HONGQIANG;YIN, FENG;KANG, SISHUN;GU, CHENGYUN;LIU, LIJUN;WANG, DONGMEI;WANG, GUOXIANG |
发明人 |
CAI, SUIXIONG;TIAN, YE EDWARD;DONG, HAIJUN;XIE, KAI;LI, SICUN;WANG, BIN;ZHANG, XIUYAN;KONG, LINGSHENG;FEI, HONGQIANG;YIN, FENG;KANG, SISHUN;GU, CHENGYUN;LIU, LIJUN;WANG, DONGMEI;WANG, GUOXIANG |
