发明名称 CD3-BINDING MOLECULES CAPABLE OF BINDING TO HUMAN AND NON-HUMAN CD3
摘要 The present invention relates to CD3 -binding molecules capable of binding to human and non-human CD3, and in particular to such molecules that are cross-reactive with CD3 of a non-human mammal (e.g., a cynomolgus monkey). The invention also pertains to uses of such antibodies and antigen-binding fragments in the treatment of cancer, autoimmune and/or inflammatory diseases and other conditions.
申请公布号 CA2836857(A1) 申请公布日期 2012.11.29
申请号 CA20122836857 申请日期 2012.05.16
申请人 MACROGENICS, INC. 发明人 HUANG, LING;JOHNSON, LESLIE S.
分类号 C07K16/28;C07K16/46 主分类号 C07K16/28
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