发明名称 ALBUMIN-BOUND PROTEIN/PEPTIDE COMPLEX AS BIOMARKER FOR DISEASE
摘要 <P>PROBLEM TO BE SOLVED: To provide a method of diagnosing a disease or disorder comprising measuring the level of albumin-bound protein/peptide complex(es) (ABPPC). <P>SOLUTION: A method comprises the steps of screening serum ABPPCs in a population of patients having a specific disease or disorder (myocardial ischemia, myocardial infarction, or vasculitis), and comparing the ABPPCs thus identified with the ABPPCs in a normal subject population. The biomarkers can be detected using, for example, a protein assay, a binding assay, or an immunoassay. The biomarkers may also be identified as peaks using mass spectroscopy, or as gel bands using, for example, size exclusion chromatography, optionally after appropriate initial treatment of the sample. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012233907(A) 申请公布日期 2012.11.29
申请号 JP20120151290 申请日期 2012.07.05
申请人 JOHNS HOPKINS UNIV 发明人 JENNIFER E VAN EYK;REBEKAH LYNN GUNDRY;ROBERT J COTTER
分类号 G01N33/68;C07K14/76;G01N33/15;G01N33/50 主分类号 G01N33/68
代理机构 代理人
主权项
地址