发明名称 GLUTATHIONE ALKYLESTER ISOTOPOLOGUE AND METHOD FOR DETECTING REACTIVE METABOLITE
摘要 <p>[Problem] To provide a novel isotope-labeled compound that can be used as a trapping agent and that is useful for picking out drug-candidate compounds that produce reactive metabolites. [Solution] Provided is a glutathione alkylester isotopologue represented by general formula (1). In formula (1), R1 represents a C1-8 linear or branched alkoxy group in which at least one of the carbon atom(s), oxygen atom(s), and hydrogen atom(s) is isotope-labeled or a C1-8 cycloalkoxy group in which at least one of the carbon atom(s), oxygen atom(s), and hydrogen atom(s) is isotope-labeled.</p>
申请公布号 WO2012160798(A1) 申请公布日期 2012.11.29
申请号 WO2012JP03302 申请日期 2012.05.21
申请人 KYORIN PHARMACEUTICAL CO., LTD.;YAMAOKA, TOSHIKAZU 发明人 YAMAOKA, TOSHIKAZU
分类号 C07K5/037;C07B59/00;G01N27/62 主分类号 C07K5/037
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