发明名称 |
PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER |
摘要 |
According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing a cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity to a partial polypeptide of CAPRIN-1, which is represented by any of even-numbered sequences of SEQ ID NOS: 2 to 30, wherein the polypeptide has the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence.
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申请公布号 |
US2012301476(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
US201113576969 |
申请日期 |
2011.02.04 |
申请人 |
OKANO FUMIYOSHI;SAITO TAKANORI;KOBAYASHI SHINICHI;IDO TAKAYOSHI;NARITA YOSHINORI |
发明人 |
OKANO FUMIYOSHI;SAITO TAKANORI;KOBAYASHI SHINICHI;IDO TAKAYOSHI;NARITA YOSHINORI |
分类号 |
A61K39/395;A61P35/00;C07K16/30 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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