发明名称 AMYLOID BETA ANTIBODY FOR USE IN IMPROVING COGNITION
摘要 <P>PROBLEM TO BE SOLVED: To provide improved agents and methods for treatment of diseases associated with &beta; amyloid (A&beta;). <P>SOLUTION: The invention features selection of A&beta; antibodies having particular activities, in particular, the ability to preferentially bind to soluble, oligomeric A&beta; and/or the ability to rapidly improve cognition as determined in an appropriate animal of A&beta; related cognitive deficit. Preferred agents include antibodies, e.g., humanized antibodies specific for A&beta;. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012233002(A) 申请公布日期 2012.11.29
申请号 JP20120172572 申请日期 2012.08.03
申请人 JANSSEN ALZHEIMER IMMUNOTHERAPY;WYETH LLC 发明人 JACOBSON JACK STEVEN
分类号 A61K39/395;A61P25/28;C07K16/18 主分类号 A61K39/395
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