发明名称 |
Compositions and methods for reduced scarring and for treatment of fibrosis |
摘要 |
Embodiments of the present disclosure are directed to methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic molecular agent selected from the group consisting of an agent that inhibits chaperonin containing T-complex polypeptide subunit eta polypeptide ("CCT-eta"), an agent that inhibits α-Smooth Muscle Actin ("α-SMA"), or a combination thereof. In embodiments, the fibrosis may include Dupuytren's contracture, Peyronie's disease, pulmonary fibrosis, cirrhosis, interstitial lung disease or scarring alopecia. |
申请公布号 |
AU2011248566(A1) |
申请公布日期 |
2012.11.29 |
申请号 |
AU20110248566 |
申请日期 |
2011.04.28 |
申请人 |
KATHJU, SANDEEP;SATISH, LATHA;ALLEGHENY-SINGER RESEARCH INSTITUTE |
发明人 |
KATHJU, SANDEEP;SATISH, LATHA |
分类号 |
C12N15/113;A61K31/7088;A61K39/395 |
主分类号 |
C12N15/113 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|