发明名称 EGFR AND KRAS MUTATIONS FOR PREDICTION OF PATIENT RESPONSE TO EGFR INHIBITOR TREATMENT
摘要 The present invention relates to mutations in Epidermal Growth Factor Receptor (EGFR) and KRAS and methods of detecting such mutations as well as prognostic methods for identifying tumors that are susceptible to anticancer therapy such as chemotherapy and/or kinase inhibitor treatment. The methods involve determining the presence of a mutated EGFR gene or mutated EGFR protein and/or a mutated KRAS gene or mutated KRAS protein in a tumor sample.
申请公布号 EP1913157(B1) 申请公布日期 2012.11.28
申请号 EP20060773201 申请日期 2006.06.13
申请人 GENENTECH, INC. 发明人 HILLAN, KENNETH, J.
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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