发明名称 |
INTERMEDIATES OF NEUTRAL ENDOPEPTIDASE INHIBITORS AND PREPARATION METHOD THEREOF |
摘要 |
The invention relates to a new process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a g-amino-d-biphenyl-a-methylalkanoic acid, or acid ester, backbone, such as N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof. |
申请公布号 |
EP2526088(A1) |
申请公布日期 |
2012.11.28 |
申请号 |
EP20110734379 |
申请日期 |
2011.01.21 |
申请人 |
NOVARTIS AG |
发明人 |
HOOK, DAVID;ZHOU, JIANGUANG;LI, YUNZHONG;KU, JIE |
分类号 |
C07D207/277;C07D207/26;C07D207/263;C07D207/267;C07D207/38 |
主分类号 |
C07D207/277 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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