| 摘要 |
PURPOSE: A liquid formulation composition for light sensitive neutralization which will be used in a PDT procedure is provided to decompose or remove the remaining light sensitive material when the composition is applied to ALA composition for PDT treatment. CONSTITUTION: A liquid formulation composition for light sensitive neutralization which will be used in a PDT procedure comprises 0.1-1.0 wt% of xanthan gum, 0.1-20 wt% of glycerine, 16-99.2 wt% of purified water, 0.1-6.0 wt% of propylene glycol, 0.1-10 wt% of PEG, 0.1-20 wt% of sodium citrate, 0.1-2.0 wt% of sodium hydrogen carbonate, 0.1-5 wt% of sodium ascorbate, and 0.1-20 wt% of ethanol. The liquid formulation composition for light sensitive neutralization used in PDT procedure comprises the following steps: mixing xanthan gum with glycerine (S1); mixing purified water to the mixture and heating to 30-45°C (S2); adding propylene glycol and PEG-12 to the mixture and agitating for 1hour±10 minutes (S3); adding sodium citrate to the mixture and agitating for 2 hours±20 minutes(S4); adding sodium hydrogen carbonate and sodium ascorbate to the mixture and agitating 4 hours±20 minutes (S5); and adding ethanol after cooling the mixture down to room temperature (S6). [Reference numerals] (S1) Mixing xanthan gum with glycerine; (S2) Mixing purified water to the mixture and heating; (S3) Adding propylene glycol and PEG-12; (S4) Adding sodium citrate to the mixture; (S5) Adding sodium hydrogen carbonate and sodium ascorbate; (S6) Adding ethanol after cooling the mixture down to room temperature
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