发明名称 SUSBTITUTED CARBAMOLYMENTHLAMINO ACETIC ACID DERIVATIVES AS NOVEL NEP INHIBITORS
摘要 The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , A 1 , A 2 , X 1 , sand m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
申请公布号 ZA201202018(B) 申请公布日期 2012.11.28
申请号 ZA20120002018 申请日期 2012.03.19
申请人 NOVARTIS AG 发明人 IWAKI YUKI;KAWANAMI TOSHIO;KSANDER GARY MICHAEL
分类号 A61K;A61P;C07D 主分类号 A61K
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