| 发明名称 |
Substituted imidazoles as bombesin receptor subtype-3 modulators |
| 摘要 |
Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes. |
| 申请公布号 |
US8318767(B2) |
申请公布日期 |
2012.11.27 |
| 申请号 |
US201113327093 |
申请日期 |
2011.12.15 |
| 申请人 |
CHEN DAVID;FRANKLIN CHRISTOPHER L.;GUZZO PETER R.;LIN LINUS S.;LIU JIAN;LO MICHAEL M.-C.;NARGUND RAVI P.;SEBHAT IYASSU K.;MERCK SHARP & DOHME CORP;ALBANY MOLECULAR RESEARCH, INC. |
发明人 |
CHEN DAVID;FRANKLIN CHRISTOPHER L.;GUZZO PETER R.;LIN LINUS S.;LIU JIAN;LO MICHAEL M.-C.;NARGUND RAVI P.;SEBHAT IYASSU K. |
| 分类号 |
A61K31/437;A61K31/4155;A61K31/427;A61K31/4439;C07D233/64;C07D401/10;C07D401/14;C07D403/10;C07D417/10;C07D471/04 |
主分类号 |
A61K31/437 |
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