SPIROCYCLIC CYCLOPROPANE AMINO ACIDS - ANALOGUES OF GAMMA-AMINOBUTYRIC ACID, WITH LIMITED CONFORMATIONAL MOBILITY AND BASED ON THEM PHARMACEUTICAL COMPOSITIONS

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to novel spirocyclic cyclopropane amino acids of general formula I, demonstrating antipsychotic, antidepressant, anticonvulsant and anxiolytic properties. In formulaI n = 0-3, Z = CRR, R-Rrepresent hydrogen.EFFECT: invention also relates to pharmaceutical composition, containing said amino acids of general formula I.3 cl, 1 tbl, 3 ex