| 摘要 |
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y, R1, R2, R3, R4, and n are as described herein. |
| 申请人 |
GENENTECH, INC.;CURIS, INC. |
发明人 |
GUNZNER, JANET;SUTHERLIN, DANIEL;STANLEY, MARK;BAO, LIANG;CASTANEDO, GEORGETTE;LALONDE, REBECCA;WANG, SHUMEI;REYNOLDS, MARK;SAVAGE, SCOTT;MALESKY, KIMBERLY;DINA, MICHAEL;KOEHLER, MICHAEL F. T. |
