发明名称 |
Breaking immunological tolerance with a genetically encoded unnatural amino acid |
摘要 |
The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety. |
申请公布号 |
US8318172(B2) |
申请公布日期 |
2012.11.27 |
申请号 |
US20090322938 |
申请日期 |
2009.02.07 |
申请人 |
GRUNEWALD JAN;TSAO MENG-LIN;PERERA ROSHAN;LERNER RICHARD A.;SMIDER VAUGHN V.;SCHULTZ PETER G.;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
GRUNEWALD JAN;TSAO MENG-LIN;PERERA ROSHAN;LERNER RICHARD A.;SMIDER VAUGHN V.;SCHULTZ PETER G. |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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