发明名称 METHOD OF USING DEATH RECEPTOR AGONIST AND EGFR INHIBITOR
摘要 <P>PROBLEM TO BE SOLVED: To provide a drug for treating pathological condition of cancer or the like. <P>SOLUTION: There are provided a pharmaceutical preparation containing death receptor ligands including Apo-2 ligand/TRAIL polypeptides or death receptor antibodies, and EGFR inhibitors including a quinazoline derivative, and methods for using the same. The death receptor antibodies are preferably DR5 antibodies and DR4 antibodies, and the quinazoline derivative is Tarceva<SP POS="POST">TM</SP>[N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine]. Methods for using in combination with them are provided. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2012229237(A) 申请公布日期 2012.11.22
申请号 JP20120150088 申请日期 2012.07.04
申请人 GENENTECH INC 发明人
分类号 A61K45/06;A61K31/517;A61K38/00;A61K39/395;A61K47/48;A61P35/00;A61P43/00;C07K16/28;C07K16/46 主分类号 A61K45/06
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