发明名称 |
PEPTIDES, COMPOSITIONS AND USES THEREOF |
摘要 |
Described is an N-terminal hexapeptide fragment of maximakinin, QUB 698.8, which exhibits potent tissue selective actions on smooth muscle. It demonstrates a high degree of selectivity for arterial smooth muscle over small intestinal smooth muscle, causing potent relaxation of arterial smooth muscle, while causing less potent contraction of ileal smooth muscle. It may be used treatment of diseases of the cardiovascular system and in promotion of angiogenesis.
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申请公布号 |
US2012295851(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
US201213530550 |
申请日期 |
2012.06.22 |
申请人 |
SHAW CHRISTOPHER;CHEN TIANBAO;O'ROURKE MARTIN;WALKER BRIAN;HIRST DAVID;THE QUEEN'S UNIVERSITY OF BELFAST |
发明人 |
SHAW CHRISTOPHER;CHEN TIANBAO;O'ROURKE MARTIN;WALKER BRIAN;HIRST DAVID |
分类号 |
A61K38/08 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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