PRODUCTS AND PROCESSES FOR MULTIPLEX NUCLEIC ACID IDENTIFICATION
摘要
Provided herein are products and processes for detecting the presence or absence of multiple target nucleic acids. Certain methods include amplifying the target nucleic acids, or portion thereof; extending oligonucleotides that specifically hybridize to the amplicons, where the extended oligonucleotides include a capture agent; capturing the extended oligonucleotides to a solid phase via the capture agent; releasing the extended oligonucleotide by competition with a competitor; detecting the extended oligonucleotide, and thereby determining the presence or absence of each target nucleic acid by the presence or absence of the extended oligonucleotide.
申请公布号
WO2012159089(A1)
申请公布日期
2012.11.22
申请号
WO2012US38710
申请日期
2012.05.18
申请人
SEQUENOM, INC.;HONISCH, CHRISTIANE;VAN DEN BOOM, DIRK, JOHANNES;MOSKO, MICHAEL;NYGREN, ANDERS
发明人
HONISCH, CHRISTIANE;VAN DEN BOOM, DIRK, JOHANNES;MOSKO, MICHAEL;NYGREN, ANDERS