| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide dermal micro-organs (DMOs), methods and apparatuses for producing and using the same. <P>SOLUTION: The DMO including a plurality of dermal components, which substantially retain the micro-architecture and three dimensional structure of the dermal tissue from which they are derived, has dimensions selected so as to allow passive diffusion of adequate amounts of nutrients and gases to cells of the DMO and diffusion of cellular waste out of the cells so as to minimize cellular toxicity and concomitant death due to insufficient nutrition and accumulation of waste in the DMO. The invention provides the methods and apparatuses for harvesting the DMO. An apparatus for harvesting the DMO includes a support configuration to support a skin-related tissue structure from which the DMO is to be harvested, and a cutting tool able to separate the DMO from the skin-related tissue structure. <P>COPYRIGHT: (C)2013,JPO&INPIT |
