发明名称 |
CASPASE INHIBITORS |
摘要 |
A compound, or a pharmaceutically acceptable salt or ester thereof, of formula I: X—W wherein X is a caspase-selective structure and W has the structure of —NH—CH(Y)(Z) wherein Y is a structure that can form a reversible covalent bond with a caspase; and Z is selected from a carboxyl moiety or a carboxylic acid mimetic. |
申请公布号 |
US2012294843(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
US201113575273 |
申请日期 |
2011.01.27 |
申请人 |
THOMAS CRAIG;BOXER MATTHEW B. |
发明人 |
THOMAS CRAIG;BOXER MATTHEW B. |
分类号 |
A61K38/54;A61K38/06;A61P19/08;A61P29/00;A61P31/00;C07K5/08;C12N9/96;C12N9/99 |
主分类号 |
A61K38/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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