发明名称 NOVEL SUBSTITUTED BICYCLIC TRIAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS
摘要 The present invention is concerned with novel substituted bicyclic triazole derivatives of Formula (I) wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
申请公布号 US2012295901(A1) 申请公布日期 2012.11.22
申请号 US201113522430 申请日期 2011.01.12
申请人 DE CLEYN MICHEL ANNA JOZEF;VAN BRANDT SVEN FRANCISCUS ANNA;GIJSEN HENRICUS JACOBUS MARIA;BERTHELOT DIDIER JEAN-CLAUDE;OEHLRICH DANIEL 发明人 DE CLEYN MICHEL ANNA JOZEF;VAN BRANDT SVEN FRANCISCUS ANNA;GIJSEN HENRICUS JACOBUS MARIA;BERTHELOT DIDIER JEAN-CLAUDE;OEHLRICH DANIEL
分类号 A61K31/444;A61K31/437;A61K31/4985;A61K31/5383;A61P25/00;A61P25/16;A61P25/28;C07D471/04;C07D487/04;C07D498/04 主分类号 A61K31/444
代理机构 代理人
主权项
地址