METHOD AND KITS FOR THE PREDICTION OF RESPONSE/NONRESPONSE TO THE TREATMENT WITH AN ANTI-EGFR ANTIBODY IN PATIENTS WITH COLORECTAL CANCER OF ALL UICC STAGES

摘要

The invention pertains to a method for predicting responsiveness of a human patient in need of treatment with an anti-EGFR antibody to such treatment based on a biological sample. According to the invention, this method comprises: determining the mutation status of KRAS, BRAF and PIK3CA, and concluding based on the mutation status whether the subject will be responsive to treatment with an anti-EGFR antibody.