发明名称 NOVEL SUBSTITUTED TRIAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS
摘要 The present invention is concerned with novel substituted triazole derivatives of Formula (I) wherein Het1, R1, R2, A1, A2, A3, A4, L1, and L2 have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
申请公布号 US2012295891(A1) 申请公布日期 2012.11.22
申请号 US201113522409 申请日期 2011.01.12
申请人 VAN BRANDT SVEN FRANCISCUS ANNA;DE CLEYN MICHEL ANNA JOZEF;GIJSEN HENRICUS JACOBUS MARIA;BERTHELOT DIDIER JEAN-CLAUDE;SURKYN MICHEL 发明人 VAN BRANDT SVEN FRANCISCUS ANNA;DE CLEYN MICHEL ANNA JOZEF;GIJSEN HENRICUS JACOBUS MARIA;BERTHELOT DIDIER JEAN-CLAUDE;SURKYN MICHEL
分类号 A61K31/4196;A61K31/454;A61K31/496;A61K31/5377;A61K31/551;A61P25/28;C07D401/14;C07D403/12;C07D403/14;C07D413/14 主分类号 A61K31/4196
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