| 发明名称 |
N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS |
| 摘要 |
Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
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| 申请公布号 |
US2012296072(A1) |
申请公布日期 |
2012.11.22 |
| 申请号 |
US201213565447 |
申请日期 |
2012.08.02 |
| 申请人 |
KINSTLER OLAF B.;GABRIEL NANCY ELISE;FARRAR CHRISTINE E.;DEPRINCE RANDOLPH B.;AMGEN INC. |
发明人 |
KINSTLER OLAF B.;GABRIEL NANCY ELISE;FARRAR CHRISTINE E.;DEPRINCE RANDOLPH B. |
| 分类号 |
A61K38/21;C07K1/113;A61K31/00;A61K38/00;A61K38/19;A61K47/30;A61K47/48;A61P1/16;A61P3/06;A61P7/00;A61P7/06;A61P9/10;A61P25/00;A61P31/12;A61P35/00;A61P37/00;A61P37/04;C07K;C07K1/06;C07K1/107;C07K1/13;C07K14/52;C07K14/53;C07K14/535;C07K14/555;C07K14/56;C07K17/08 |
主分类号 |
A61K38/21 |
| 代理机构 |
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