发明名称 |
METHOD FOR PREDICTING EFFECTIVENESS OF ANGIOGENESIS INHIBITOR |
摘要 |
The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject affected by a tumor. Provided is a method comprising a step of testing for the presence or absence of an expression deficiency or a mutation in B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of an expression deficiency or a mutation in B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject. |
申请公布号 |
WO2012157672(A1) |
申请公布日期 |
2012.11.22 |
申请号 |
WO2012JP62509 |
申请日期 |
2012.05.16 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD.;SEMBA TARO;NARITA YUSUKE;MINOSHIMA YUKINORI;YAMAGUCHI ATSUMI;ADACHI YUSUKE;YAMADA KAZUHIKO;MATSUI JUNJI;KADOWAKI TADASHI;TAKAHASHI KENTARO;FUNAHASHI YASUHIRO |
发明人 |
SEMBA TARO;NARITA YUSUKE;MINOSHIMA YUKINORI;YAMAGUCHI ATSUMI;ADACHI YUSUKE;YAMADA KAZUHIKO;MATSUI JUNJI;KADOWAKI TADASHI;TAKAHASHI KENTARO;FUNAHASHI YASUHIRO |
分类号 |
C12Q1/68;A61K31/47;A61P35/00;A61P43/00;C12N15/09;G01N33/15;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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