The invention pertains to a method for early detection and screening of colorectal cancer in human subjects based on RNA isolated from blood obtained from said subject. According to the invention, the abundance of at least 300 RNAs listed in table 1 is measured. Using the invention, an accurate and noninvasive screening and diagnosis tool for colorectal cancer is provided with a sensitivity of at least 70 % and a specificity of 75 % that has high clinical utility and the potential for broad adoption.
申请公布号
WO2012156530(A1)
申请公布日期
2012.11.22
申请号
WO2012EP59340
申请日期
2012.05.21
申请人
SIGNATURE DIAGNOSTICS AG;ADAMS, HANS-PETER;HINZMANN, BERND;MAYR, TOBIAS;ROSENTHAL, ANDRE
发明人
ADAMS, HANS-PETER;HINZMANN, BERND;MAYR, TOBIAS;ROSENTHAL, ANDRE