COMPOSITION COMPRISING ENDOSTATIN AND RNAI MOLECULES AND THE USE THEREOF
摘要
<p>The invention discloses a composition and the use thereof, wherein the composition comprises endostatin which serves as a delivery system and chemically synthesized RNAi molecules. The composition comprises endostatin recombinant protein which carries +5 to +15 charges and chemically synthesized RNAi molecules which have - 15 to -55 charges, and the combination of the positive and negative charges from the two makes the composition acquire -20 to +20 charges.</p>
申请公布号
WO2012155328(A1)
申请公布日期
2012.11.22
申请号
WO2011CN74100
申请日期
2011.05.16
申请人
NANJING UNIVERSITY;JIANGSU RESEARCH CENTER FOR GENE PHARMACEUTICAL ENGINEERING AND TECHNOLOGY;XU, GENXING;YIN, YAN;GUO, JIAJIA;ZHANG, CHANGDONG;WU, ZHIWEI