| 发明名称 |
1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS |
| 摘要 |
The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
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| 申请公布号 |
CA2832384(A1) |
申请公布日期 |
2012.11.22 |
| 申请号 |
CA20122832384 |
申请日期 |
2012.05.11 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;SIENA BIOTECH S.P.A |
发明人 |
HILPERT, HANS;NARQUIZIAN, ROBERT;PINARD, EMMANUEL;POLARA, ALESSANDRA;ROGERS-EVANS, MARK;WOLTERING, THOMAS;WOSTL, WOLFGANG |
| 分类号 |
C07D265/08;A61K31/535;A61K31/5355;A61P25/28;C07D413/10;C07D413/12 |
主分类号 |
C07D265/08 |
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