| 发明名称 |
4-hydroxythiobenzamide derivatives of drugs |
| 摘要 |
Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both. |
| 申请公布号 |
US8314140(B2) |
申请公布日期 |
2012.11.20 |
| 申请号 |
US20070374273 |
申请日期 |
2007.07.18 |
| 申请人 |
WALLACE JOHN;CIRINO GIUSEPPE;SANTAGADA VINCENZO;CALIENDO GIUSEPPE;ANTIBE THERAPEUTICS INC. |
发明人 |
WALLACE JOHN;CIRINO GIUSEPPE;SANTAGADA VINCENZO;CALIENDO GIUSEPPE |
| 分类号 |
A61K31/405;A61K31/35;A61K31/40;C07C61/04;C07C321/00;C07D207/00;C07D209/00;C07D309/30;C07D313/04 |
主分类号 |
A61K31/405 |
| 代理机构 |
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代理人 |
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