发明名称 |
Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters |
摘要 |
The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters, 2-(aminomethylidene)-4,4-difluoro-3-oxobutteric esters of the formula (I) in which R1, R2 and R3 independently of one another are C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C10-cycloalkyl or benzyl or NR2R3 is a 5- to 10-membered heterocyclic radical, to a process for preparing compounds of the formula (I) wherein an appropriate 3-aminoacrylic ester is reacted with difluoroacetyl fluoride and to the use of compounds of the formula (I) in the process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters. |
申请公布号 |
US8314233(B2) |
申请公布日期 |
2012.11.20 |
申请号 |
US20090990359 |
申请日期 |
2009.04.30 |
申请人 |
ZIERKE THOMAS;MAYWALD VOLKER;RACK MICHAEL;SMIDT SEBASTIAN PEER;KEIL MICHAEL;WOLF BERND;KORADIN CHRISTOPHER;BASF SE |
发明人 |
ZIERKE THOMAS;MAYWALD VOLKER;RACK MICHAEL;SMIDT SEBASTIAN PEER;KEIL MICHAEL;WOLF BERND;KORADIN CHRISTOPHER |
分类号 |
C07D295/145;C07D211/34;C07D265/30 |
主分类号 |
C07D295/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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