发明名称 |
URINE RISEDRONATE EVALUATION BY SPE/LC-MS/MS |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention concerns a method of SPE/LC-MS/MS for urine risedronate evaluation. The method involves: a) adding an internal standard solution to an urine sample; b) applying the urine sample on a processed chromatographic column followed by risedronate elution in vacuum; e) evaporating the eluted solution and dissolving for preparing a sample in the form of mixed risedronate and the internal standard; f) analysing the mixture sample in a system of high-pressure liquid chromatography - mass spectrometry/mass spectrometry (LC-MS/MS). ^ EFFECT: provided risedronate evaluation in the urine sample. ^ 16 cl, 4 tbl, 6 dwg |
申请公布号 |
RU2467332(C2) |
申请公布日期 |
2012.11.20 |
申请号 |
RU20090136989 |
申请日期 |
2008.03.05 |
申请人 |
SANOFI-AVENTIS JU.EHS. EHLEHLSI |
发明人 |
SHEHN' LIDO;LU JUNI |
分类号 |
B01D15/36;G01N30/00;G01N33/52 |
主分类号 |
B01D15/36 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|