METHOD OF OBTAINING POLYALKYLENEGLYCOL ESTERS OF -TOCOFEROL

摘要

FIELD: chemistry. ^ SUBSTANCE: invention relates to method of obtaining polyalkyleneglycol esters of -tocoferol, applied in cosmetology, medicine and food industry. Method lies in interaction of -tocoferol acetate with alkali, ethylene oxide or propylene oxide at temperature 100-175C and pressure 1-5 atm. Process is carried out in two stages. At the first stage interaction of -tocoferol with alkali and ethylene oxide or propylene oxide is performed. Oxide is used in amount 2-10 moles per a mole of -tocoferol acetate. Obtained product is separated. At the second stage selected intermediate product is oxyakylated with ethylene and/or propylene oxide on presence of alkali. ^ EFFECT: invention makes it possible to obtain water-soluble polyalkyleneglycol esters of -tocoferol, which do not contain inorganic admixtures. ^ 2 cl, 2 tbl, 12 ex