发明名称 4-[4-({[4-CHLOR-3-(TRIFLUOROMETHYL)PHENYL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE MONOHYDRATE
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to monohydrate of 4-[4-({[4-chlor-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide of formula (II) method of its obtaining, to application of claimed compound for obtaining medication for treatment of hyperproliferative diseases and to pharmaceutical composition for treatment of hyperproliferative disease, which includes formula II compound. ^ EFFECT: obtained and described is novel compound, which can be useful in application for control of hyperproliferative diaseses. ^ 9 cl, 1 ex, 7 tbl, 7 dwg
申请公布号 RU2466992(C2) 申请公布日期 2012.11.20
申请号 RU20090117388 申请日期 2007.09.29
申请人 BAJER SHERING FARMA AKTSIENGEZEL'SHAFT 发明人 GRUNENBERG AL'FONS;SHTIL' JURGEN;TENBIG KATARINA;KAJL' BIRGIT
分类号 A61K31/44;A61K35/00;C07D213/81 主分类号 A61K31/44
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