摘要 |
FIELD: medicine. ^ SUBSTANCE: group of invention refers to a polypeptide composition containing one or more polypeptides which are immunogenic in a vertebrate so that they induce production in the vertebrate of cells of the immune system able to recognize at least one epitope in a protein fraction of arthropod's saliva with the protein fraction of arthropod's saliva having weight of 20 kDa or less, while the polypeptides are independently specified in a polypeptide sequence SEQ ID NO:1-44 or having 7 amino acids or more partial sequences, methods for making it, using for preparing a drug. ^ EFFECT: group of invention is effective in treating or preventing a disease propagated by arthropods. ^ 44 cl, 10 dwg, 21 tbl, 4 ex |