摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, and concerns a diagnostic technique for prostate cancer involving sample analysis for the presence and/or the amount of annexin A3 with using a monoclonal antibody specific to annexin A3 of low cross reactivity to the other annexins and aiming at an N-terminal of annexin A3, especially on an epitope in the region of amino acid of 1-16 human annexin A3. Also, the invention refers to a reagent for diagnosing prostate cancer containing such antibodies. ^ EFFECT: invention provides a technique for detecting prostate carcinoma enabling high-specific early diagnosis. ^ 9 cl, 5 ex, 15 dwg |