发明名称 METHOD OF ANALYSING MASS SPECTRUM FOR DIAGNOSING CANCER USING CANCER-SPECIFIC GLYCANS AND THEIR DERIVATIVES
摘要 PURPOSE: A method for analyzing mass spectrum for cancer diagnosis is provided to enhance specificity and sensitivity. CONSTITUTION: A method for analyzing mass spectrum for cancer diagnosis comprises: a step of determining a plurality of markers using peaks of first spectrum of one or more glycans from blood of a patient with cancer and peaks of second spectrum of one or more glycans from blood of a patient with cancer(S1); a step of comparing the first and seconds peaks and determining boundary value for each marker(S2); a step of comparing the intensity of plural third peaks corresponding to each marker with the boundary value(S3); a step of determining each third peak is patient tendency or normal tendency(S4); and a step of acquiring cancer progress information of the sample using the number of peaks determined as the patient tendency and normal tendency(S5). [Reference numerals] (AA) Start; (BB) Finish; (S1) Drawing first and second mass spectrum of one or more glycans from blood of cancer patient and healthy person; (S2) Determining one or more probes using peaks of first and second spectrum; (S3) Determining boundary value of peak intensity by comparing peaks corresponding to probe at first and second mass spectrum; (S4) Drawing third mass spectrum from blood of test subject; (S5) Comparing peak intensity corresponding to probe with broundary value at third mass spectrum and acquiring cancer progression information of the test subject
申请公布号 KR101202585(B1) 申请公布日期 2012.11.19
申请号 KR20120018940 申请日期 2012.02.24
申请人 发明人
分类号 G01N33/66;G01N27/62 主分类号 G01N33/66
代理机构 代理人
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