发明名称 |
Højkoncentreret antistofholdig væskeformulering |
摘要 |
The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine. |
申请公布号 |
DK2238985(T3) |
申请公布日期 |
2012.11.19 |
申请号 |
DK20080866971T |
申请日期 |
2008.12.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG |
发明人 |
MORICHIKA, TOSHIYUKI;KAMEOKA, DAISUKE;IMAEDA, YOSHIMI;MAEDA, TERUTOSHI;STAUCH, OLIVER BORIS |
分类号 |
A61K9/08;A61K39/395;A61K47/18;A61P43/00 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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