发明名称 |
Materials and Methods Related to Sodium/Potassium Adenosine Triphosphate and Cholesterol |
摘要 |
This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream.
|
申请公布号 |
US2012289479(A1) |
申请公布日期 |
2012.11.15 |
申请号 |
US201113521864 |
申请日期 |
2011.01.13 |
申请人 |
XIE ZI-JIAN;CHEN YILIANG;WANG HAOJIE;UNIVERSITY OF TOLEDO |
发明人 |
XIE ZI-JIAN;CHEN YILIANG;WANG HAOJIE |
分类号 |
A61K31/566;A61K31/724;A61P3/06;A61P25/28;C12N5/071;G01N33/53;G01N33/573 |
主分类号 |
A61K31/566 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|