| 发明名称 |
NITRIC OXIDE/CGMP PATHWAY INHIBITION OF VLA-4 RELATED CELL ADHESION |
| 摘要 |
The invention provides methods of treating nitric oxide/cGMP pathway-cell adhesion disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention relates to a method for down-regulating a4ß1-integrin affinity and inhibiting and reversing adhesion formation in patients or subjects in need using a nitric oxide donor. |
| 申请公布号 |
WO2012154975(A2) |
申请公布日期 |
2012.11.15 |
| 申请号 |
WO2012US37352 |
申请日期 |
2012.05.10 |
| 申请人 |
STC.UNM;CHIGAEV, ALEXANDRE;SKLAR, LARRY, A. |
发明人 |
CHIGAEV, ALEXANDRE;SKLAR, LARRY, A. |
| 分类号 |
A61K31/4162;A61K31/34;A61K31/506;A61K31/519;A61K31/52;A61P35/00 |
主分类号 |
A61K31/4162 |
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