摘要 |
<p>A method of increasing insulin content in a pancreatic beta cell is disclosed. The method comprising expressing in the pancreatic beta cell an exogenous polynucleotide encoding at least one microRNA or a precursor thereof, wherein the microRNA is selected from the group consisting of miR-15, miR-16, miR-24, miR-26, miR-27, miR- 29, miR-30, miR-129, miR-141, miR-148, miR-182, miR-200, miR-376 and Let-7, thereby increasing the insulin content in the pancreatic beta cell.</p> |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;HORNSTEIN, ERAN;MELKMAN-ZEHAVI, TAL;OREN, RONI |
发明人 |
HORNSTEIN, ERAN;MELKMAN-ZEHAVI, TAL;OREN, RONI |