TENOMODULIN (TNMD) ISOFORMS AND USES THEREOF

摘要

The presently disclosed subject matter relates to tenomodulin (TNMD) and its isoforms. Also described are diagnostic and therapeutic uses of tenomodulin (TNMD) and its isoforms, such as in connective tissues such as tendon. More particularly, provided herein are methods of detecting a tenomodulin polypeptide, methods of detecting a nucleic acid molecule that encodes a tenomodulin polypeptide, and methods of modulating the biological activity of a tenomodulin polypeptide.